Do inhibitors of the renin–angiotensin system prevent chronic kidney disease?
نویسنده
چکیده
The world is facing an epidemic of chronic kidney disease (CKD) and in South Africa, death rates from end-stage renal disease (ESRD) have risen by 68% from 1999 to 2006.
منابع مشابه
Study of chronic effect of Losartan in inhibition of kidney glomerular number and glomerular volume changes in uninephrectomized diabetic rats(Stereological study).
Background: Diabetic nephropathy is one of the cause of the end stage of renal disease (ESRD). Hyperglicemia activate intrarenal Renin-Angiotensin system and highly AngiotensinII is produced locally in glomeruli. In this research AT1(Angiotensin type 1) receptors blocked by Losartan and effects of this drug in inhibition of renal structural lesions were assessed quantitatively. Materials & me...
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عنوان ژورنال:
دوره 21 شماره
صفحات -
تاریخ انتشار 2010